Polynucleotide
Salmon DNA (PDRN)

Advanced Rejuran treatment for smoother, firmer, youthful skin.

The Treatment Process

Consultation:

Your journey begins with a detailed consultation at the clinic, where we assess your skin and design a personalized plan.

Treatment Session:

Sessions last 30-40 minutes. Both numbing cream and lidocaine injections are used to ensure patients' comfort during the treatment. Our doctor uses the canula method to deliver polynucleotides precisely into targeted areas.

Aftercare:

Mild redness or swelling may appear but fades within 1–2 days. Our team provides comprehensive aftercare instructions with special focus on sun protection in Israel’s climate.

Follow-Up:

A series of 2-4 treatments is typically recommended, followed by maintenance sessions once a year to preserve results.

Polynucleotide Salmon DNA therapy, also known as PDRN injections, is considered a revolutionary approach in modern aesthetic medicine. While many people refer to it as the "Salmon Sperm" treatment, the correct name is Polynucleotide (PN) therapy.

This advanced method goes beyond simply reducing the visible signs of aging. By working at the cellular level, Polynucleotide injections help restore skin health, improve elasticity, and stimulate natural regeneration processes.

Unlike temporary fillers, which only add volume for a limited time, Polynucleotide Salmon DNA (PDRN) treatments improve the skin’s long-term quality from within.

Many patients who have undergone this treatment at Kayla Daniel’s clinic in Israel report noticeable improvements in their skin’s texture, elasticity, hydration levels and overall skin health.

Expected Results: The Benefits of Salmon DNA Treatment

The Salmon DNA treatment is a groundbreaking, highly sought-after skin rejuvenation procedure. It goes beyond addressing external signs of aging, working at a cellular level to regenerate and repair the skin from within.

Clients at our clinic consistently report significant improvements:

Deep Skin Restoration: The active ingredients, called polynucleotides, stimulate skin cells to boost the production of collagen and elastin, the fundamental building blocks of firm, youthful skin.
Protection from Environmental Damage: The treatment acts as a shield against free radicals, helping to preserve healthy cells and maintain a younger-looking complexion.
Significant Reduction in Fine Lines and Wrinkles: By improving the skin's elasticity and texture, you'll notice a gradual reduction in fine lines, especially around the eyes and mouth.
Even and Healthy Skin Tone: This treatment improves overall skin quality and can help reduce the appearance of acne scars and pigmentation.
Natural and Revitalized Look: Unlike treatments that add volume, this procedure enhances the skin's natural renewal processes, giving you a vibrant and glowing look without appearing "overdone" or artificial.
Long-Lasting Hydration: The hydrophilic molecules in the DNA effectively bind water, creating a "moisture reservoir" that keeps your skin supple, soft, and radiant.
High Safety Profile: Since the treatment is based on natural, biological materials, the risk of allergic reactions is low, making it suitable even for delicate areas like the neck and eyelids.

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Consultations & Bookings

Frequently Asked Questions About the Salmon DNA Facial Treatment (Polynucleotide / PDRN)

What is the Salmon DNA facial treatment (Polynucleotide / PDRN) and how does it work?

The Salmon DNA facial treatment – also known as a Polypeptide or PDRN injection – involves injecting purified DNA fragments derived from salmon into the skin. These fragments are biologically compatible and act as messengers, stimulating fibroblast cells to produce new collagen and elastin, increasing blood flow, and promoting deep tissue repair. Unlike filler treatments that simply add temporary volume, this approach enhances skin health from within and restores a naturally firm and radiant appearance.

Who is the Salmon DNA facial treatment suitable for and what are the benefits?

This treatment is ideal for women and men who want to reduce fine lines, improve thin or dry skin, address pigmentation or acne scars, or achieve an overall glow. Salmon DNA injections are also suitable for delicate areas such as around the eyes, the neck and the décolletage. The benefits include increased collagen and elastin production, reduced inflammation, improved skin elasticity, fewer wrinkles and scars, enhanced hydration and a more even tone. It is not recommended during pregnancy or nursing, and it should be avoided by individuals with fish allergies or active skin infections.

How many sessions are needed and when will I see results from a Salmon DNA injection?

A course of two to tree sessions, spaced approximately two to four weeks apart, is usually recommended. After the first session you may notice greater luminosity and hydration within several days, but collagen production takes time. A significant improvement in texture, evenness and fine lines typically becomes noticeable four to eight weeks after starting the treatment. Patience is important because the process relies on natural skin regeneration.

How long do the results of a Salmon DNA injection last and what maintenance is required?

Following a full series of treatments, results generally last about six to twelve months. The duration depends on factors like skin condition, age and lifestyle; excessive sun exposure or smoking can shorten the effects. A maintenance treatment once a year helps sustain the improvement. Unlike hyaluronic acid fillers, Salmon DNA injections produce longer-lasting results by enhancing collagen and elastin production rather than simply filling in volume.

What happens during a Salmon DNA facial injection and how long does the procedure take?

A consultation and skin assessment is the first step. During the procedure, a doctor uses a cannula or fine needle with a numbing cream, making the experience mildly uncomfortable at most. The treatment typically takes 30 to 45 minutes, after which you can return to your daily activities. Mild redness or swelling at the injection sites may appear but usually resolves within a day or two.

Does the Salmon DNA facial treatment hurt and are there any side effects?

Most people experience little discomfort due to the combination of numbing cream and a very fine cannula. Side effects are usually minor and include temporary redness, slight swelling or tiny bruises at the injection points, all of which subside within 24–48 hours. Allergic reactions to salmon-derived ingredients are rare but possible, so it is essential to inform the doctor about any sensitivities before beginning treatment.

How should I prepare for a Salmon DNA injection and what is the recovery like?

Minimal preparation is required. It is advisable to avoid blood-thinning medications and limit alcohol intake for a couple of days before the procedure. After the injection, you should:

Avoid strenuous exercise, saunas or hot baths for 24 hours.
Use gentle cleansers and apply unscented moisturizer.
Wear broad-spectrum sunscreen and limit sun exposure for several days.
Refrain from rubbing the treated area or applying heavy makeup the day after.
Recovery is quick, allowing most patients to resume normal routines immediately.

What is the difference between a Salmon DNA injection, hyaluronic acid fillers and Botox?

Botox works by relaxing the muscles that cause dynamic wrinkles, and its effects are temporary. Hyaluronic acid fillers add volume to specific areas but gradually dissolve. Salmon DNA injections, also known as Polynucleotide or PDRN treatments, operate on a different principle: they stimulate the skin to renew itself, boost collagen and elastin production, and improve texture and tone. The result is natural and long-lasting, and the procedure can be combined with fillers or Botox for a comprehensive, personalized plan.

How much does the Salmon DNA facial treatment cost in Israel?

In Israel, a single session of the Salmon DNA facial treatment typically starts around 3,000 NIS and can reach approximately 3,500 NIS, depending on the amount of product used, the condition of your skin, and the clinic’s expertise. A full course of three to four treatments may cost between 7,000 and 15,000 NIS. An annual maintenance session is generally priced similarly to an individual treatment. It is advisable to obtain a tailored quote following a professional consultation.

Why choose Salmon DNA injections for facial rejuvenation?

Salmon DNA injections offer a cutting-edge biological solution for skin rejuvenation. They strengthen and restore the skin from within, improve elasticity, replenish moisture and brightness, reduce wrinkles and scars, and deliver a natural look without artificial fullness. With a high safety profile and minimal downtime, this treatment is ideal for those seeking long-term and profound skin renewal.